PromPDD were developed based on the prediction models generated using the average relative binding (ARB) matrix method.PromPDD enables the prediction and deciphering of promiscuous peptides that bind to multiple HLA molecules within or cross HLA supertypes in a simpler and more direct way. We expanded the application of PromPDD to HLA class I alleles with limited experimentally verified data by generating pan-specific matrices using a derived modular method, and more than 2500 HLA molecules encoded by HLA-A and -B genes are available in PromPDD.

 

 

only available for well-studied alleles in the well-defined supertypes

Input the protein sequences (plain sequences)
Length of peptide	nonamer decamer
HLA Class I Supertype	Choose Supertype A1 A2 A3 A24 B7 B44 B58 B27 B62

 

Input the protein sequences (plain sequences)
Length of peptide	nonamer decamer
Select alleles	HLA-A*01:01 HLA-A*01:07 HLA-A*01:23 HLA-A*01:28 HLA-A*01:72 HLA-A*01:98 HLA-A*02:01 HLA-A*02:02 HLA-A*02:03 HLA-A*02:05 HLA-A*02:06 HLA-A*02:104 HLA-A*02:11 HLA-A*02:12 HLA-A*02:14 HLA-A*02:142 HLA-A*02:16 HLA-A*02:17 HLA-A*02:172 HLA-A*02:179 HLA-A*02:184 HLA-A*02:19 HLA-A*02:195 HLA-A*02:22 HLA-A*02:232 HLA-A*02:271 HLA-A*02:286 HLA-A*02:324 HLA-A*02:337 HLA-A*02:344 HLA-A*02:355 HLA-A*02:359 HLA-A*02:36 HLA-A*02:382 HLA-A*02:413 HLA-A*02:421 HLA-A*02:433 HLA-A*02:44 HLA-A*02:484 HLA-A*02:489 HLA-A*02:495 HLA-A*02:496 HLA-A*02:507 HLA-A*02:532 HLA-A*02:54 HLA-A*02:546 HLA-A*02:572 HLA-A*02:58 HLA-A*02:591 HLA-A*02:593 HLA-A*02:78 HLA-A*03:01 HLA-A*03:08 HLA-A*03:105 HLA-A*03:107 HLA-A*03:12 HLA-A*03:173 HLA-A*03:231 HLA-A*03:41 HLA-A*03:57 HLA-A*03:88 HLA-A*11:01 HLA-A*11:04 HLA-A*11:10 HLA-A*11:111 HLA-A*11:130 HLA-A*11:199 HLA-A*11:222 HLA-A*11:223 HLA-A*11:25 HLA-A*11:38 HLA-A*11:39 HLA-A*23:01 HLA-A*23:04 HLA-A*23:40 HLA-A*24:02 HLA-A*24:03 HLA-A*24:207 HLA-A*24:302 HLA-A*24:94 HLA-A*25:01 HLA-A*26:01 HLA-A*26:02 HLA-A*26:03 HLA-A*26:05 HLA-A*26:09 HLA-A*29:02 HLA-A*30:01 HLA-A*30:02 HLA-A*30:57 HLA-A*31:01 HLA-A*31:21 HLA-A*31:25 HLA-A*31:66 HLA-A*32:01 HLA-A*32:07 HLA-A*32:24 HLA-A*32:26 HLA-A*32:42 HLA-A*33:01 HLA-A*33:03 HLA-A*33:06 HLA-A*33:100 HLA-A*33:101 HLA-A*33:103 HLA-A*33:104 HLA-A*33:105 HLA-A*33:11 HLA-A*33:12 HLA-A*33:14 HLA-A*33:15 HLA-A*33:20 HLA-A*33:23 HLA-A*33:25 HLA-A*33:26 HLA-A*33:29 HLA-A*33:30 HLA-A*33:31 HLA-A*33:33 HLA-A*33:35 HLA-A*33:36 HLA-A*33:37 HLA-A*33:39 HLA-A*33:40 HLA-A*33:43 HLA-A*33:44 HLA-A*33:45 HLA-A*33:46 HLA-A*33:47 HLA-A*33:51 HLA-A*33:52 HLA-A*33:54 HLA-A*33:55 HLA-A*33:56 HLA-A*33:57 HLA-A*33:58 HLA-A*33:61 HLA-A*33:62 HLA-A*33:63 HLA-A*33:65 HLA-A*33:70 HLA-A*33:71 HLA-A*33:72 HLA-A*33:75 HLA-A*33:76 HLA-A*33:77 HLA-A*33:79 HLA-A*33:81 HLA-A*33:82 HLA-A*33:83 HLA-A*33:84 HLA-A*33:85 HLA-A*33:86 HLA-A*33:88 HLA-A*33:90 HLA-A*33:93 HLA-A*33:95 HLA-A*33:97 HLA-A*33:99 HLA-A*34:02 HLA-A*34:03 HLA-A*34:04 HLA-A*34:09 HLA-A*34:13 HLA-A*36:02 HLA-A*36:04 HLA-A*68:01 HLA-A*68:02 HLA-A*68:31 HLA-A*68:54 HLA-A*68:61 HLA-A*68:66 HLA-A*69:01 HLA-A*74:01 HLA-A*74:02 HLA-A*74:03 HLA-A*74:04 HLA-A*74:07 HLA-A*74:08 HLA-A*74:09 HLA-A*74:11 HLA-A*74:15 HLA-A*74:16 HLA-A*74:17 HLA-A*74:18 HLA-A*74:20 HLA-A*74:22 HLA-A*74:24 HLA-A*74:25 HLA-A*74:26 HLA-A*74:27 HLA-A*80:01 HLA-A*80:02 HLA-B*07:02 HLA-B*07:24 HLA-B*07:31 HLA-B*07:60 HLA-B*08:01 HLA-B*15:01 HLA-B*15:03 HLA-B*15:05 HLA-B*15:107 HLA-B*15:114 HLA-B*15:117 HLA-B*15:14 HLA-B*15:154 HLA-B*15:165 HLA-B*15:17 HLA-B*15:179 HLA-B*15:186 HLA-B*15:20 HLA-B*15:212 HLA-B*15:241 HLA-B*15:275 HLA-B*15:332 HLA-B*15:51 HLA-B*15:52 HLA-B*15:53 HLA-B*15:85 HLA-B*18:01 HLA-B*18:10 HLA-B*18:105 HLA-B*18:11 HLA-B*18:110 HLA-B*18:113 HLA-B*18:19 HLA-B*18:35 HLA-B*18:36 HLA-B*18:58 HLA-B*18:69 HLA-B*18:97 HLA-B*27:05 HLA-B*27:38 HLA-B*35:01 HLA-B*35:102 HLA-B*35:115 HLA-B*35:118 HLA-B*35:14 HLA-B*35:15 HLA-B*35:190 HLA-B*35:22 HLA-B*35:24 HLA-B*35:260 HLA-B*35:287 HLA-B*35:31 HLA-B*35:32 HLA-B*35:35 HLA-B*35:43 HLA-B*35:63 HLA-B*35:67 HLA-B*35:68 HLA-B*35:79 HLA-B*35:86 HLA-B*35:93 HLA-B*39:01 HLA-B*39:07 HLA-B*39:15 HLA-B*39:30 HLA-B*39:48 HLA-B*40:01 HLA-B*40:02 HLA-B*40:164 HLA-B*40:20 HLA-B*40:21 HLA-B*40:210 HLA-B*40:219 HLA-B*40:229 HLA-B*40:40 HLA-B*40:49 HLA-B*40:63 HLA-B*40:92 HLA-B*44:02 HLA-B*44:03 HLA-B*44:103 HLA-B*44:14 HLA-B*44:146 HLA-B*44:16 HLA-B*44:188 HLA-B*44:212 HLA-B*44:37 HLA-B*44:55 HLA-B*44:64 HLA-B*44:91 HLA-B*45:01 HLA-B*45:04 HLA-B*45:10 HLA-B*46:01 HLA-B*48:01 HLA-B*51:01 HLA-B*51:02 HLA-B*51:101 HLA-B*51:143 HLA-B*51:146 HLA-B*51:180 HLA-B*51:199 HLA-B*51:21 HLA-B*51:34 HLA-B*53:01 HLA-B*53:02 HLA-B*54:01 HLA-B*54:03 HLA-B*54:26 HLA-B*55:10 HLA-B*56:16 HLA-B*57:01 HLA-B*58:01 HLA-B*58:14 HLA-B*58:36 HLA-B*58:64
or type allele names (ie HLA-A0101,HLA-A0201) separated by commas..
For list of allowed allele names click here List of HLA allele names.

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Input the sequence of peptide (9-mer or10-mer) example: "FLPSDFFPSV"
HLA Class I Supertype	Choose Supertype A1 A2 A3 A24 B7 B44 B58 B27 B62

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